At least 21 people were killed, and 100 more were injured after two high-speed trains collided in southern Spain on Sunday, according to officials.

A train travelling from Málaga to Madrid derailed near Adamuz, crossing over to the adjacent track where it hit another train coming from Madrid to Huelva, according to the Spanish Interior Minister.

Officials said that of the 100 people injured, at least 25 of them suffered serious injuries.

Rescue crews are on the scene, and all trains between Madrid and the Andalusia region are suspended, according to officials.

The cause of the train derailment has not yet been released.

This is a developing story. Please check back for updates.