The United States launched dozens of against ISIS targets in central Syria on Sunday in an attempt to “disrupt, degrade and defeat” the terrorist group, according to the head of the U.S. Central Command.

CENTCOM Commander Gen. Michael Erik Kurilla said in a statement that 75 ISIS targets were hit in precision airstrikes Sunday in Syria. He said the mission was carried out by U.S. Air Force assets, including B-52s, F-15s and A-10s.

“There should be no doubt — we will not allow ISIS to reconstitute and take advantage of the current situation in Syria. All organizations in Syria should know that we will hold them accountable if they partner with or support ISIS in any way,” Kurilla said.

Kurilla said the strikes hit known ISIS camps and operatives in central Syria.

During a speech at the White House on Sunday, President Joe Biden mentioned the U.S. strikes on ISIS targets in Syria. He said U.S. forces are also bolstering security at detention facilities in Syria where ISIS fighters are being held.

“We’re clear-eyed about the fact that ISIS will try to take advantage of any vacuum to reestablish its capability and to create a safe haven,” Biden said. “We will not let that happen.”

-ABC News’ Cindy Smith